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Monday, August 3, 2020 | History

2 edition of Antigens of rat and mouse epidermis. found in the catalog.

Antigens of rat and mouse epidermis.

Olavi RaМ€saМ€nen

Antigens of rat and mouse epidermis.

Immunoelectrophoretic, double gel diffusion, and immunofluorescence studies.

by Olavi RaМ€saМ€nen

  • 244 Want to read
  • 1 Currently reading

Published by Munksgaard in Copenhagen .
Written in English

    Subjects:
  • Antigens.,
  • Epidermis.,
  • Rats -- Physiology.,
  • Mice -- Physiology.

  • Edition Notes

    Bibliography: p. 77-81.

    SeriesActa pathologica et microbiologica Scandinavica. Supplementum, 198
    Classifications
    LC ClassificationsQR185.A6 R3
    The Physical Object
    Pagination81 p.
    Number of Pages81
    ID Numbers
    Open LibraryOL5725317M
    LC Control Number70456111

    A possible mode of UV-B action is that it exerts adverse effects on antigen-presenting cell function. Because the epidermis is the only tissue that is naturally subject to UV exposure we investigated if murine epidermal cells (EC) could perform an antigen presentation function and, if so, could this function be altered by UV-B irradiation. Solanum tuberosum L. cv Jayoung Epidermis Extract Inhibits Mite Antigen-Induced Atopic Dermatitis in NC/Nga Mice by Regulating the Th1/Th2 Balance and Expression of Filaggrin J Med Food. Sep;18(9) doi: /jmf

      To track EPC fate in normal epidermis we have used inducible genetic marking to label a sample of cells and their progeny in adult mice. Animals transgenic for . The origins and functions of resident immune cells in barrier tissue are highly diverse. Lin et al. identify in the zebrafish epidermis an ectoderm-derived immune cell type—metaphocytes—that capture soluble antigens from external environment through transepithelial protrusions and convey these antigens to conventional Langerhans cells via an apoptosis-phagocytosis pathway.

    Metastatic melanoma remains incurable, emphasizing the acute need for improved research models to investigate the underlying biologic mechanisms mediating tumor invasion and metastasis, and to develop more effective targeted therapies to improve clinical outcome. Available animal models of melanoma . A murine monoclonal antibody, LICR-LON, which had been raised against a well-differentiated squamous cell carcinoma cell line (LICR-LON-HN5), recognises an antigen which is present on the membrane of basal cells of the epidermis. The tissue distribution of the antigen, as .


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Antigens of rat and mouse epidermis by Olavi RaМ€saМ€nen Download PDF EPUB FB2

Antigens of rat and mouse epidermis. Immunoelectrophoretic, double gel diffusion, and immunofluorescence studies. Räsänen, Antigens of rat and mouse epidermis Acta Pathol Microbiol Scand Suppl () 9.

R.J. Ablin, Immunopathologic studies of experimental pemphigus-like autoantibodies and bullous-like lesions J Invest Dermatol () Cited by: Abstract. Pemphigus vulgaris is an autoimmune disease associated with an autoantibody directed against a keratinocyte membrane antigen.

The purpose of this study was to purify the human pemphigus vulgaris antigen, to produce an antibody to this antigen, and to use the antibody to induce pemphigus in newborn by:   Original Article Immunohistochemical Identification of Skn Antigens In Mouse Epidermis Susan H.

Jackman, Elizabeth S. De Pirro, Ellen H. Goldberg, Department of Microbiology, University of New Mexico, School of Medicine, Albuquerque, New Mexico, U.S.A.

Department of Microbiology, University of New Mexico, School of Medicine Albuquerque New Mexico U.S.A. Rejection of murine Cited by: 7. Tissue-specific antigen deletion is a feature of experimental and human tumours, including squamous cell carcinomas in man and mouse.

The patterns of Author: H.K. Muller, R.C. Sutherland. The epidermis is a stratified epithelium which regenerates continuously throughout the life of the organism. In humans, it is estimated that the epidermis turns over every 40–56 days 1, 2, whereas in mice the estimated epidermal turnover time is 8–10 days constant turnover of the epidermis is mediated by epidermal stem cells, which reside in the basal layer of the epidermis 4.

LCs are highly specialized antigen-presenting cells that account for approximately 2–4% of the total epidermal cell population in both mice and humans (Valladeau and Saeland, ).

They are characterized as the intraepithelial subpopulation of DCs, which have distinct functions from dermal DCs. Human epidermis probably also contains specific antigens corresponding to the eight found in rat epidermis ("'Ex ), most of which disappear in e.g.

chemical carcinogenesis of the skin, but remain to be present in well differentiated squamous epithelial tumours con taining keratinpearls (RASANEN ). Flank (mouse, rat, rabbit) or dorsal ear (pig) skin tissue was excised for testing immediately post euthanasia (mouse/rat with CO 2 chamber, rabbits and pigs with overdose of ketamine/xylazine.

IFN-γ transgenic mice develop a nonblistering inflammatory skin disease with dermal edema and have marked splenomegaly. In addition, serum from the transgenic mice contains antibodies that produce a nuclear pattern of staining on sections of normal mouse epidermis. In view of these findings, we investigated IFN-γ transgenic mice for the.

Interestingly, the epidermis of these mice did not show extensive spontaneous lesions. However, when a female DSG3 −/− mouse delivered pups, their suckling caused erosions around the nipples (Fig. 3, C) and some mice showed crusting on the skin around the eyes and snout (Fig.

3, D), areas that are normally traumatized by scratching. At P3 the epidermis of KCre/Ikk2 FL/FL mice showed upregulation of keratin 6 (K6) expression, a marker for inflamed and hyperproliferative epidermis, and suprabasal expression of.

Immunostaining of skin sections revealed strong expression of SCCA1 in the upper epidermis of the transgenic mice, but not in the skin of wild-type HR-1 mice. When mJ/cm 2 UV was irradiated twice on the backs of mice, the epidermis of wild-type HR-1 mice was seriously damaged, as seen in loss of the granular layer and spongiosis in the.

Acta Pathol Microbiol Scand. Antigens of rat and mouse epidermis. Immunoelectrophoretic, double gel diffusion, and immunofluorescence studies. IFN-gamma transgenic mice develop a lupus-like syndrome. Involucrin is a component of the keratinocyte cell envelope and its expression is essentially limited to the suprabasal layers of stratified squamous epithelia [].In order to study the role of IFN-γ in the pathogenesis of inflammatory skin disease, we generated transgenic mice expressing the cytokine under the influence of the.

calcitriol alters expression of filaggrin but not keratin K1 in mouse epidermis. PMID: Acute or chronic topical retinoic acid treatment of human skin in vivo alters the expression of epidermal transglutaminase, loricrin, involucrin, filaggrin, and keratins 6 and 13.

In contrast, by 7 days after excision, the rat epidermis transits over a matrix containing both mouse and rat fibronectin, or rat fibronectin alone, indicating that a major component of the.

Human CD antigens 28 Human non-CD antigens 52 Mouse CD antigens 57 Mouse non-CD antigens 76 Abbreviations Act Activated ASV Alternative splice variants ADCC Antibody-dependent cellular cytotoxicity AML Acute myeloid leukemia APC Antigen presenting cells BM Bone marrow CCRSF Complement component receptor superfamily CD Cluster of differentiation.

The macrophage-specific antigen F4/80 has been localized in mouse lymphoid and hematopoietic tissue and skin using immunoperoxidase staining. The antigen permits identification of early mononuclear phagocyte precursors in the bone marrow, and is present also on larger cells forming the center of hematopoietic islands and lining vascular sinuses.

a process is presented for the culture of clinical stafilococcus epidermidis cells whose reproduction allows the identification of a limited number of predominating serotypes. the two common predominating serotypes have been identified most of the clinical cases of s. epidermidis and have been designated type i and type ii.

there is an antigen tensioactive polisacarids associated with each of. Tissue Distribution and Cellular Expression of Ia Antigens 3. Monoclonal Antibodies Against Murine Ia Antigens: Studies on Structure, Function, Epitodes, and Idiotypes 4. Functional Characterization of Hybrid Ia Antigens 5.

Murine Ia Antigens: Studies Using Hybrid and Mutant Mice 6. Carbohydrate Ia antigens in Mouse and Man 7.Antigen capturing in the skin and antigen trafficking into regional lymph nodes (LN) initiate immune responses. In this study, employing melanin granule (MG) as an easily traceable antigen in two mouse strains that carried steel factor or hepatocyte growth factor transgenes and had melanocytosis in the epidermis or in the dermis respectively.Mice were vaccinated with a cell wall protein preparation of S.

epidermidis. A highly immunodominant antigen was identified as Accumulation-associated protein (Aap). mAbs against Aap and against.